Tagging single muons and other long-flying relativistic charged particles by ultra-fast timing in air Cherenkov telescopes

Atmospheric air Cherenkov telescopes are successfully used for ground-based, very high-energy (VHE) gamma ray astronomy. Triggers from the so-called single muon and other long-flying relativistic charged particle events are an unwanted background for the Cherenkov telescope. Because of low rate at TeV energies the muon background is unimportant. It is much more intense for telescopes with high photon sensitivity and low energy threshold. Below a few hundred GeV energy, the so-called muon background becomes so intense, that it can deteriorate the sensitivity of telescopes (the so-called muon-wall problem). From general considerations it can be anticipated that the signature of these particles should be a light pulse with a narrow time structure. In fact, simulations show that the pulses from muons have a very narrow time profile that is well below the time resolutions of nearly all currently operating telescopes. In this report we elaborate on the time profile of Cherenkov light from the so-called single muons and show that a telescope with ultra-fast time response can open a new dimension allowing one to tag and to reject those events.Comment: Accepted by Astroparticle Physic

bNAber: database of broadly neutralizing HIV antibodies.

The discovery of broadly neutralizing antibodies (bNAbs) has provided an enormous impetus to the HIV vaccine research and to entire immunology. The bNAber database at http://bNAber.org provides open, user-friendly access to detailed data on the rapidly growing list of HIV bNAbs, including neutralization profiles, sequences and three-dimensional structures (when available). It also provides an extensive list of visualization and analysis tools, such as heatmaps to analyse neutralization data as well as structure and sequence viewers to correlate bNAbs properties with structural and sequence features of individual antibodies. The goal of the bNAber database is to enable researchers in this field to easily compare and analyse available information on bNAbs thereby supporting efforts to design an effective vaccine for HIV/AIDS. The bNAber database not only provides easy access to data that currently is scattered in the Supplementary Materials sections of individual papers, but also contributes to the development of general standards of data that have to be presented with the discovery of new bNAbs and a universal mechanism of how such data can be shared

Detection Techniques of Microsecond Gamma-Ray Bursts using Ground-Based Telescopes

Gamma-ray observations above 200 MeV are conventionally made by satellite-based detectors. The EGRET detector on the Compton Gamma Ray Observatory (CGRO) has provided good sensitivity for the detection of bursts lasting for more than 200 ms. Theoretical predictions of high-energy gamma-ray bursts produced by quantum-mechanical decay of primordial black holes (Hawking 1971) suggest the emission of bursts on shorter time scales. The final stage of a primordial black hole results in a burst of gamma-rays, peaking around 250 MeV and lasting for a tenth of a microsecond or longer depending on particle physics. In this work we show that there is an observational window using ground-based imaging Cherenkov detectors to measure gamma-ray burst emission at energies E greater than 200 MeV. This technique, with a sensitivity for bursts lasting nanoseconds to several microseconds, is based on the detection of multi-photon-initiated air showers.Comment: accepted for publication in the Astrophysical Journa

Variability in the high energy gamma ray emission from Cyg X-3 over a two-year period (1983 - 1984) at E 4 x 10(11) eV

Cygnus X-3 is observed to emit gamma rays with energies in excess of 4 x 10 to the 11th power eV during two out of 9 observational categories over an 18 month time span. The emissions are observed at the 0.6 phase of the characteristic 4.8 hr light curve for this binary system. We estimate a peak flux at phase 0.6 of 5 x 10 to the minus 10th power photons cm-2s-1 at a software threshold of 8 x 10 to the 11th power eV for Oct/Nov 1983. A flux for the June 84 effect cannot be reliably calculated at present due to lack of Monte Carlo simulations for the energy range and spectral region. For the other 7 observational categories the observations are consistent with zero source emission. The light curve would appear to be variable on a time scale of a couple of weeks at these categories. Selection of compact images in accordance with Monte Carlo simulations combined with empirical optimization techniques have led to an enriched gamma ray light curve for the Oct/Nov 1983 data. Selection on the basis of shower orientation, however, has not led to any notable enhancement of the gamma ray content. Individual Cherenko images can be reliably sorted on an event by event basis into either proton-induced or photon-induced showers

ANN-based energy reconstruction procedure for TACTIC gamma-ray telescope and its comparison with other conventional methods

The energy estimation procedures employed by different groups, for determining the energy of the primary $\gamma$-ray using a single atmospheric Cherenkov imaging telescope, include methods like polynomial fitting in SIZE and DISTANCE, general least square fitting and look-up table based interpolation. A novel energy reconstruction procedure, based on the utilization of Artificial Neural Network (ANN), has been developed for the TACTIC atmospheric Cherenkov imaging telescope. The procedure uses a 3:30:1 ANN configuration with resilient backpropagation algorithm to estimate the energy of a $\gamma$-ray like event on the basis of its image SIZE, DISTANCE and zenith angle. The new ANN-based energy reconstruction method, apart from yielding an energy resolution of $\sim$ 26%, which is comparable to that of other single imaging telescopes, has the added advantage that it considers zenith angle dependence as well. Details of the ANN-based energy estimation procedure along with its comparative performance with other conventional energy reconstruction methods are presented in the paper and the results indicate that amongst all the methods considered in this work, ANN method yields the best results. The performance of the ANN-based energy reconstruction has also been validated by determining the energy spectrum of the Crab Nebula in the energy range 1-16 TeV, as measured by the TACTIC telescope.Comment: 23pages, 9 figures Accepted for publication in NIM

Is the EGRET source 3EG J1621+8203 the radio galaxy NGC 6251?

We discuss the nature of the unidentified EGRET source 3EG J1621+8203. In an effort to identify the gamma-ray source, we have examined X-ray images of the field from ROSAT PSPC, ROSAT HRI, and ASCA GIS. Of the several faint X-ray point sources in the error circle of 3EG J1621+8203, most are stars or faint radio sources, unlikely to be counterparts to the EGRET source. The most notable object in the gamma-ray error box is the bright FR I radio galaxy NGC 6251. If 3EG J1621+8203 corresponds to NGC 6251, then it would be the second radio galaxy to be detected in high energy gamma rays, after Cen A, which provided the first clear evidence of the detection above 100 MeV of an AGN with a large-inclination jet. If the detection of more radio galaxies by EGRET has been limited by its threshold sensitivity, there exists the exciting possibility that new high energy gamma-ray instruments, with much higher sensitivity, will detect a larger number of radio galaxies in the future.Comment: 7 pages, 6 figures. Accepted for publication in The Astrophysical Journal, August 2002 issu

Search for gamma-rays above 400 GeV from Geminga

Observations of Geminga made at the Whipple Observatory using the atmospheric Cherenkov technique during the moonless periods of November 1983 to February 1984 and November 1984 till February 1985 were examined for evidence for the emission of gamma rays with energy in excess of approx 400 GeV. Evidence of either a steady flux or a flux pulsed with a period near 60 seconds were studied. In neither case was any significant effect observed, enabling the establishment 3 of sigma upper limits of 5.5 x 10 to the -11th power photons/sq cm/s and 2.0 x 10 to the -11th power photons/sq cm/s for the steady and pulsed emission respectively. The limit to the pulsed flux is approximately a factor of six below that predicted

Trance Logic, Age Regression, and Incomplete Responding: A Preliminary Investigation of Contextual Influences

Fifty-four hypnotizable and 49 unhypnotizable simulating subjects were age regressed to age five and asked to write the sentence “I am participating in a psychological experiment” embedded in either “standard” suggestions for regression or in the context of a suggested dream. As predicted, hypnotizable subjects were sensitive to the context manipulation (i.e., dream vs. standard), evidencing more correct or “adult” spelling (“trance logic”) during age regression when the dream context encouraged a melding of fantasy and reality. Simulators’ performance was stable across conditions. Consistent with the hypothesis that incomplete responding is at the heart of incongruous spelling during age regression, the hypnotizable and simulating subjects who evinced the least compelling experiences of age regression were the most likely to spell “adult” words correctly (exhibit “trance logic”). Finally, none of the 31 subjects whose handwriting was rated as “childlike and primitive” spelled the word “psychological” correctly, providing clear evidence that subjects who were the most responsive to the age regression suggestion fail to exhibit trance logic